[Download] "Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy" by Emmanuel Donnadieu # eBook PDF Kindle ePub Free

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eBook details

• Title: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
• Author : Emmanuel Donnadieu
• Release Date : January 30, 2016
• Genre: Medical,Books,Professional & Technical,Science & Nature,Life Sciences,
• Pages : * pages
• Size : 3420 KB

Description

This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.

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